THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING / MCGILL UNIVERSITY
发明人:
TRIFIRO, MARK,PALIOURAS, MILTIADIS,ROCHE, PHILIP,DOTAN, IDIT,BEITEL, LENORE,CARNEVALE, MATTHEW,MITMAKER, ELLIOT JONATHAN,ALVARADO, CARLOS
申请号：
CA2930441
公开号：
CA2930441A1
申请日:
2014.11.14
申请国别(地区):
CA
年份:
2015
代理人:
摘要：
There is provided a bionanofluid including a carbon-based nanomaterial substantially mono-dispersed in a fluid, wherein the carbon-based nanomaterial is surface modified with a polar group when the fluid is polar or with a non-polar group when the fluid is non-polar, and functionalized with a biological targeting moiety to allow specific association of the carbon-based nanomaterial to a targeted entity. Also provided is a hybrid bionanofluid including the bionanofluid, wherein the carbon-based nanomaterial is further modified with a hybrid nanoparticle which includes an alloy, transition metal, semi-conductor, semi- metal or polymer based nanoparticle with biological targeting moiety. A hydrogel, foam, cream, spray or dried product including the bionanofluid or hybrid bionanofluid is also provided. The bionanofluid or hybrid bionanofluid are useful in multimodal imaging (photo-luminescence, luminescence, photo-acoustic, MRI, ultrasound) and/or cellular targeting.
