INDUSTRIAL RESEARCH LIMITED;ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY
发明人:
CLINCH, KEITH,EVANS, GARY BRIAN,FURNEAUX, RICHARD HUBERT,KELLY, PETER MICHAEL,SCHRAMM, VERN L.,TYLER, PETER CHARLES,WOOLHOUSE, ANTHONY DAVID,GULAB, SHIVALI ASHWIN
申请号：
CA2662628
公开号：
CA2662628C
申请日:
2007.09.07
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
The invention relates to compounds of the general formula (l) whichare inhibitors of purine nucleoside phosphorylases (PNPs) and/or nucleosidehydrolases (NHs). The invention also relates to the use of these compoundsin the treatment of diseases and infections including cancer, bacterialinfections, protozoal infections, and T-cell mediated disease and topharmaceutical compositions containing the compounds.(see formula I)
