Immune synthesis of Streptococcus injection, including 1, 4, 5, 6b, 7F, 9V, 14, 18C, 22F, 23F and other serum aggregating sacs, including the combination of a conjugate and PTD； including vaccine； manufacturing process； for Disease Prevention (div.sol. N.3625-2006)
BIEMANS, RALPH LEON,GARCON, NATHALIE MARIE- JOSEPHE,HERMAND, PHILIPPE VINCENT,POOLMA, JAN,VAN MECHELEN, MARCELLE PAULETTE
申请号：
CL2013002106
公开号：
CL2013002106A1
申请日:
2013.07.23
申请国别(地区):
CL
年份:
2014
代理人:
摘要：
The present invention is in the field of pneumococcal capsular saccharide conjugate vaccines. Specifically, a multivalent Streptococcus pneumoniae immunogenic composition is provided comprising 10 or more capsular saccharides from different S. pneumoniae serotypes which are conjugated to a carrier protein, and comprising 3 or more different carrier proteins, wherein the composition comprises: serotype 19F capsular saccharide conjugated to diphtheria toxoid (DT)； serotype 18C capsular saccharide conjugated to tetanus toxoid (TT)； serotype 1,4,5,6B,7F,9V,14 and 23F capsular saccharides conjugated to protein D from Haemophilus influenzae .COMPOSICIÓN INMUNOGÉNICA DE STREPTOCOCCUS PNEUMONIAE QUE COMPRENDE SACÁRIDOS CAPSULARES DE LOS SEROTIPOS 1, 4, 5, 6B, 7F, 9V, 14, 18C, 22F Y 23F CONJUGADOS Y COMPRENDE UN CONJUGADO CON PHTD A TRAVÉS DE UN ENGARCE； VACUNA QUE LA COMPRENDE； PROCEDIMIENTO DE FABRICACIÓN； Y SU USO PARA PREVENIR ENFERMEDADES (DIV.SOL.N°3625-2006)
