PROCÉDÉS DE PRÉVENTION DE L'ALLO-IMMUNISATION DES PLAQUETTES ET DE LA RÉFRACTIVITÉ DES PLAQUETTES ALLO-IMMUNES ET DE L'INDUCTION DE LA TOLÉRANCE CHEZ LES RECEVEURS TRANSFUSÉS
Methods and compositions for the prevention or reduction of platelet transfusion associated complications are provided. The subject methods include modifying donor whole blood or platelets prior to transfusion to prevent or reduce alloimmune platelet refractoriness.