PROCEDES DE PREVENTION DE L'ALLO-IMMUNISATION DES PLAQUETTES ET DE LA REFRACTIVITE DES PLAQUETTES ALLO-IMMUNES ET DE L'INDUCTION DE LA TOLERANCE CHEZ LES RECEVEURS TRANSFUSES
Methods and compositions for the prevention or reduction of platelet transfusion associated complications are provided. The subject methods include modifying donor whole blood or platelets prior to transfusion to prevent or reduce alloimmune platelet refractoriness.