INSTITUTO FINLAY. CENTRO DE INVESTIGACION-PRODUCCION DE VACUNAS Y SUEROS;CENTRO NACIONAL DE BIOPREPARADOS
发明人:
LASTRE GONZÁLEZ, MIRIAM DE SAN JUAN BOSCO,RODRÍGUEZ MARTÍNEZ, CLAUDIO,SIERRA GONZÁLEZ, VICTORIANO, GUSTAVO,PÉREZ MARTÍN, OLIVER GERMÁN,BIDOT MARTÍNEZ IGOR,PÉREZ LASTRE, JORGE, ERNESTO,BRACHO GRANADO,
申请号：
MYPI 20031710
公开号：
MY146106A
申请日:
2003.05.07
申请国别(地区):
MY
年份:
2012
代理人:
摘要：
THE PRESENT INVENTION RELATES TO THE FIELD OF IMMUNOLOGY, SPECIFICALLY WITH THE BRANCH OF IMMUNO-ALLERGY AND IN PARTICULAR WITH THE USE OF ADJUVANT OR CARRIER COMPOUNDS, CAPABLE OF MODULATING THE IMMUNE RESPONSE TO ALLERGENS. THE TECHNICAL OBJECTIVE THAT IS PURSUED IS TO OBTAIN A PHARMACEUTICAL PREPARATION OF THERAPEUTIC OR PROPHYLACTIC USE USING BACTERIAL PROTEOLIPOSOMES, WHICH TRANSFORM THE ALLERGIC RESPONSE TH2 AND IGE WHEN BEING APPLIED IN ALLERGIC INDIVIDUALS, TOWARDS A PROTECTOR RESPONSE TH1； AS WELL AS IT IS ABLE TO PREVENT THE APPEARANCE AND THE DEVELOPMENT OF ALLERGIES IN INDIVIDUALS NON-ALLERGIC YET. THE VACCINE COMPOSITION CONSISTS OF PROTEOLIPOSOMES DERIVED FROM GRAM-NEGATIVE BACTERIA COUPLED TO ALLERGENS AND OPTIONALLY CONTAINS OTHER ADJUVANTS OR ANTIGENS. THE METHOD FOR ITS PREPARATION AND AN IMMUNIZATION SCHEME OF TWO DOSES ARE PROVIDED.
