composition, method, risk reduction method, prevention or treatment of an individual having an autoimmune disease or disorder, method of inducing degradation of a target protein in a cell, method for reducing risk, preventing or treating a disease state or disorder in a patient wherein the unregulated protein activity is responsible for said disease or condition, method for reducing the risk, preventing or treating cancer in an individual, and method of treating a genetic disease or disorder in an individual
INC.;H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE
发明人:
HARSHANI LAWRENCE,NICHOLAS J. LAWRENCE,PEARLIE BURNETTE
申请号：
BR112018068906
公开号：
BR112018068906A2
申请日:
2017.03.16
申请国别(地区):
BR
年份:
2019
代理人:
摘要：
These are small molecules against cereblon to enhance effector t-cell function. Methods of producing these molecules and methods of using them to treat various disease states are also disclosed.trata-se de pequenas moléculas contra cereblon para intensificar função de célula t efetora. são revelados também métodos de produção destas moléculas e métodos de uso das mesmas para tratar vários estados da doença.
