Eric L. Brown;Hiroaki Taguchi;Stephanie Planque;Sudhir Paul;Yasuhiro Nishiyama;Keri C. Smith
发明人:
Sudhir Paul,Stephanie Planque,Yasuhiro Nishiyama,Eric L. Brown,Keri C. Smith,Hiroaki Taguchi
申请号:
US12589440
公开号:
US09969797B2
申请日:
2009.10.23
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Disclosed are antibodies (immunoglobulins) and fragments thereof that hydrolyze or bind polypeptide antigens belonging to Staphyloccus aureus, hepatitis C virus, human immunodeficiency virus and Alzheimer's disease. Also disclosed are novel methods to improve the antigen reactivity of the immunoglobulins and to treat a pathophysiological condition using the immunoglobulins as therapeutics.