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Erythrocyte-binding therapeutics
专利权人:
Karen Y. Dane;Jeffrey A. Hubbell;Stéphane Kontos
发明人:
Jeffrey A. Hubbell,Stéphane Kontos,Karen Y. Dane
申请号:
US13397202
公开号:
US09517257B2
申请日:
2012.02.15
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Peptides that specifically bind erythrocytes are described. These are provided as peptidic ligands having sequences that specifically bind, or as antibodies or fragments thereof that provide specific binding, to erythrocytes. The peptides may be prepared as molecular fusions with therapeutic agents, tolerizing antigens, or targeting peptides. Immunotolerance may be created by use of the fusions and choice of an antigen on a substance for which tolerance is desired.
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