Khvorova, Anastasia,Salomon, William,Kamens, Joanne,Samarsky, Dmitry,Woolf, Tod M.,Cardia, James,Pavco, Pamela A.,Libertine, Lyn,Bulock, Karen G.
申请号:
AU2018202014
公开号:
AU2018202014A1
申请日:
2018.03.21
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
#$%^&*AU2018202014A120180510.pdf#####ABSTRACT The present invention relates to RNAi constructs with improved tissue and cellular uptake characteristics and methods of use of these compounds in dermal and fibrotic applications. dsRNA formulated according to the invention includes self-delivering RNA, or sd-rxRNA, molecules and rxRNAori molecules.