Oil-in-water emulsions that contain nucleic acids

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专利权人:

Novartis AG

发明人:

BRITO, Luis,CHAN, Michelle,GEALL, Andrew,O'HAGAN, Derek,SINGH, Manmohan,OHAGAN, Derek

申请号：

AU2017200640

公开号：

AU2017200640A1

申请日:

2017.01.31

申请国别(地区):

AU

年份:

2017

代理人:

摘要：

#$%^&*AU2017200640A120170223.pdf#####ABSTRACT This invention generally relates to cationic oil-in-water emulsions that can be used to deliver nucleic acid molecules, such as an RNA molecule. The emulsion particles comprise an oil core and a cationic lipid. The emulsion particles have an average diameter of about 80 nm to about 180 nm, and the emulsion have an N/P ratio of at least 1.1:1.

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