Ulrich Heiser;Hans-Ulrich Demuth;Andre Johannes Niestroj;Torsten Hoffmann;Stephan Schilling
发明人:
Hans-Ulrich Demuth,Torsten Hoffmann,Andre Johannes Niestroj,Stephan Schilling,Ulrich Heiser
申请号：
US12101497
公开号：
US08685664B2
申请日:
2008.04.11
申请国别(地区):
US
年份:
2014
代理人:
摘要：
Novel physiological substrates of mammalian glutaminyl cyclase (QC, EC 2.3.2.5), new effectors of QC, methods for screening for such effectors, and the use of such effectors and pharmaceutical compositions comprising such effectors for the treatment of conditions that can be treated by modulation of QC-activity. Preferred compositions additionally comprise inhibitors of DP IV or DP IV-like enzymes for the treatment or alleviation of conditions that can be treated by modulation of QC- and DP IV-activity.
