BARTOLOME-NEBREDA Jose Manuel,BARTOLOME-NEBREDA Jose Manuel,MACDONALD Gregor James,MACDONALD Gregor James,VAN GOOL Michiel Luc Maria,VAN GOOL Michiel Luc Maria
申请号:
SI200931644
公开号:
SI2307374T1
申请日:
2009.07.29
申请国别(地区):
SI
年份:
2017
代理人:
摘要:
The present invention relates to piperazin-1-yl-trifluoromethyl-substituted-pyridines that are fast dissociating dopamine 2 receptor antagonists, processes for preparing these compounds, pharmaceutical compositions comprising these compounds as an active ingredient. The compounds find utility as medicines for treating or preventing central nervous system disorders, for example schizophrenia, by exerting an antipsychotic effect without motor side effects.