The present invention provides a local medication composition of coffee-bean extract, which includes the effectively-dosed coffee-bean extract and the medically-acceptable locally-used carrier. The present invention provides a coffee-bean extract used in the manufacturing the medicament with application in the healing of the wound. The present invention verifies that the miscellaneous coffee-bean extract not only has better capability of removing the free radicals and anti-oxidation, but also has the efficacy in expediting the wound healing, therefore capable of being used as the raw material of medicaments promoting the healing of wound, which has highly economic value and the advantage of mass production.本發明提供一種咖啡豆萃取物之局部用藥組成物,包含有效劑量之咖啡豆萃取物以及其藥學上可接受之局部用載劑。本發明提供一種咖啡豆萃取物用於製造促進傷口癒合之醫藥品的用途。本發明證實各種咖啡豆萃取物不但具有較佳的清除自由基、抗氧化之能力,且皆具有加速傷口癒合的效力。其作為促進傷口癒合醫藥品之原料係具有高經濟價值且可大量生產之優勢。