Tyukalova Lyudmila Ivanovna,Тюкалова Людмила Ивановна,Sotnikova Larisa Stepanovna,Сотникова Лариса Степановна,Pavlova Irina Borisovna,Павлова Ирина Борисовна,Lapteva Evgeniya Viktorovna,Лаптева Евгени
申请号：
RU2015131859/14
公开号：
RU0002596056C1
申请日:
2015.07.30
申请国别(地区):
RU
年份:
2016
代理人:
摘要：
FIELD: medicine.SUBSTANCE: invention relates to medicine and can be used for clinical assessment of probability of developing non-massive pulmonary artery thromboembolia (PATE) in patients, receiving menopausal hormone therapy. Clinical signs are determined and following signs are assessed in points: existence of receiving menopausal hormonal therapy agents, appearance on ECG signs of pulmonary heart, presence in Doppler echocardiography signs of right ventricular dysfunction detection in x-ray image of chest signs of pulmonary heart, presence of congenital or acquired disorders hemostasis, from laboratory indicators, such as homocysteine, presence of blood markers of APL syndrome, product of dehydration of fibrin D-dimer above 500 ng/ml, change on side of coagulation system (coagulation and/or platelet haemostasis), occurrence of signs of chronic venous insufficiency for period of using menopausal hormonal therapy, presence of metabolic syndrome, absence of any of following clinical signs is evaluated as 0 points. Obtained points are summed up. If total score is more than 19 a high probability of developing non-massive PATE is determined. If total score ranges from 13 to 18 - moderate probability of developing PATE. If total score is less than 12 - low clinical probability of non-massive PATE.EFFECT: method improves accuracy and information value of detection of non-massive PATE in females, receiving menopausal hormonal therapy.1 cl, 2 tblИзобретение относится к области медицины и может быть использовано для клинического определения вероятности развития немассивной тромбоэмболии легочной артерии (ТЭЛА) у пациенток, принимающих менопаузальную гормонотерапию. Выполняют определение клинических признаков и оценивают в баллах следующие признаки: наличие факта приема средств менопаузальной гормональной терапии, появление на ЭКГ признаков легочного сердца, наличие при допплер-эхокардиографии признаков нарушения функции правого желудочка, выявление при рентгенографии орган
