LEYSEN, DIRK,DEFERT, OLIVIER,BOLAND, SANDRO,ALEN, JO,BOURIN, ARNAUD PIERRE JEAN
申请号:
CA2834387
公开号:
CA2834387A1
申请日:
2012.04.27
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
The present invention relates to new kinase inhibitors, more specifically ROCK inhibitors, compositions, in particular pharmaceuticals, comprising such inhibitors, and to uses of such inhibitors in the treatment and prophylaxis of disease. In particular, the present invention relates to new ROCK inhibitors, compositions, in particular pharmaceuticals, comprising such inhibitors, and to uses of such inhibitors in the treatment and prophylaxis of disease. In addition, the invention relates to methods of treatment and use of said compounds in the manufacture of a medicament for the application to a number of therapeutic indications including sexual dysfunction, inflammatory diseases, ophthalmic diseases and Respiratory diseases.