Jo Alen;Olivier Defert;Sandro Boland;Dirk Leysen;Arnaud Pierre Jean Bourin
发明人:
Jo Alen,Sandro Boland,Arnaud Pierre Jean Bourin,Olivier Defert,Dirk Leysen
申请号：
US14241092
公开号：
US09079858B2
申请日:
2012.08.31
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The present invention relates to new kinase inhibitors, more specifically ROCK inhibitors, compositions, in particular pharmaceuticals, comprising such inhibitors, and to uses of such inhibitors in the treatment and prophylaxis of disease. In particular, the present invention relates to new ROCK inhibitors, compositions, in particular pharmaceuticals, comprising such inhibitors, and to uses of such inhibitors in the treatment and prophylaxis of disease. In addition, the invention relates to methods of treatment and use of said compounds in the manufacture of a medicament for the application to a number of therapeutic indications including sexual dysfunction, inflammatory diseases, ophthalmic diseases and respiratory diseases.
