The invention provides an ultraviolet disinfection device, which comprises a body, at least one ultraviolet lamp tube and at least one protection piece. The at least one ultraviolet lamp tube is respectively arranged on at least one lamp holder module of the body, the at least one protection piece is moved on the body, and is located on one side of the corresponding ultraviolet lamp tube, and is respectively rotated with the corresponding ultraviolet lamp tube as the center.When the UV disinfection device is in use, the at least one protective part moves to the inner side of the corresponding UV lamp tube; when the UV disinfection device is not in use, the at least one protective part moves to the outer side of the corresponding UV lamp tube, and the at least one protective part protects the at least one UV lamp tube from being contaminated with dust, dust, other particles or Other pollutants also avoid the damage of at least one ultraviolet lamp tube caused by the impact of external force, so as to prolong the service life of the ultraviolet disinfection device.本創作提供一種紫外線消毒裝置,其包含一本體、至少一紫外線燈管及至少一保護件,該至少一紫外線燈管分別設置於該本體之至少一燈座模組,該至少一保護件移動設置於該本體,並位於對應之該紫外線燈管之一側,且分別以對應之該紫外線燈管為中心轉動。該紫外線消毒裝置於使用時,該至少一保護件移動至對應之該紫外線燈管之內側;該紫外線消毒裝置於未使用時,該至少一保護件移動至對應之該紫外線燈管之外側,該至少一保護件保護該至少一紫外線燈管,避免該至少一紫外線燈管沾染灰塵、粉塵、其他微粒或其他汙染物,也避免該至少一紫外線燈管受外力撞擊而損壞,以拉長該紫外線消毒裝置之使用壽命。