BOGEN STEPHANE L,WANG YAOLIN,NAIR LATHA G,VOSS MATTHEW ERNST,PAN WEIDONG,KULKARNI BHEEMASHANKAR A,LIU YUAN,RINDGEN DIANE,GUZI TIMOTHY J,NOMEIR AMIN,SHIPPS JR GERALD W,MA YAO,LAHUE BRIAN ROBERT,SHIZUKA
申请号:
ZA201202667
公开号:
ZA201202667B
申请日:
2012.04.12
申请国别(地区):
ZA
年份:
2013
代理人:
摘要:
The present invention provides a compound of Formula 1 as described herein or a pharmaceutically acceptable salt, solvate or ester thereof. The compounds are useful as inhibitors of the HDM2 protein. Also disclosed are pharmaceutical compositions comprising the above compounds and methods of treating cancer using the same.