BOGEN STEPHANE L.,MA YAO,WANG YAOLIN,LAHUE BRIAN ROBERT,NAIR LATHA G.,SHIZUKA MANAMI,VOSS MATTHEW ERNST,KIROVA-SNOVER MARGARITA,PAN WEIDONG,TIAN YUAN,KULKARNI BHEEMASHANKAR A.,GIBEAU CRAIG R.,LIU YUAN
申请号:
TN2012000129
公开号:
TN2012000129A1
申请日:
2012.03.23
申请国别(地区):
TN
年份:
2013
代理人:
摘要:
The present invention provides a compound of Formula (1) as described herein or a pharmaceutically acceptable salt, solvate or ester thereof. The compounds are useful as inhibitors of the HDM2 protein. Also disclosed are pharmaceutical compositions comprising the above compounds and methods of treating cancer using the same.