The invention provides tweezers for microsurgery, in particular opthalmological surgery, the tweezers comprising a one-piece working part (1) of U-shape, with the free ends (2a, 3a) of each branch (2, 3) being shaped into a point, the part being derived from a flat blank of thickness (e) constituting the dimension perpendicular to the plane (P) in which the branches (2, 3) move, and elements for manipulating the working part together forming a handle for gripping the tweezers, wherein each element is in the form of an elongate body (4, 5) presenting a convex outside surface (4a, 5a) and a substantially plane surface (4b, 5b) having a longitudinal groove (6, 7) hollowed out therein to house one of the branches (2, 3) of the working part (1), the end of each handle element facing towards the points being provided with centering means (8a, 8b, 9a, 9b) co-operating with a complementary centering member of the corresponding end of the other element.
