PROBLEM TO BE SOLVED: To provide an antibacterial agent that has a structure allowing structural development, and has low hemolytic activity while maintaining a wide antibacterial spectrum and high antibacterial activity.SOLUTION: A lipopeptide derivative contains a peptide sequence of Lys-Lys-Lys-Cys-Lys-Asp-Lys-Asp-Cys or a peptide sequence of Cys-Lys-Asp-Lys-Asp-Cys-Lys-Lys-Lys-NH2, and contains a plurality of alkyl chains of a hydrocarbon group comprising 8-16 carbon atoms.SELECTED DRAWING: NoneCOPYRIGHT: (C)2019,JPO&INPIT【課題】構造展開が可能な構造で、広い抗菌スペクトル及び高い抗菌活性を保持しながら低い溶血活性をもつ抗菌剤を提供する。【解決手段】LysーLysーLys-Cys-Lys-Asp-Lys-Asp-Cysのペプチド配列またはCys-Lys-Asp-Lys-Asp-Cys-LysーLysーLysーNH2のペプチド配列を含み、8から16個の炭素原子からなる炭化水素基のアルキル差を複数含むリポペプチド誘導体。【選択図】なし
