Erine Cardoso de Lima,Luiz Felipe de Oliveira Stehling,Silvana Masiero,Talitha Farina Bezerra
申请号：
US16723230
公开号：
US20200197292A1
申请日:
2019.12.20
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention refers to dermocosmetic formulations for use against skin blemishes, especially melasma. The present invention minimizes or avoids the formation of melasma by acting in several stages of melanogenesis.A preferred embodiment of the invention refers to dermocosmetic formulations that act in several stages of melanogenesis, preferably, in the gene expression of tyrosinase-related proteins (TYRP-1 and TYRP-2) and Endothelin-1 (ET-1).Another embodiment of the invention refers to the cosmetic composition containing a combination of active ingredients that act on the gene expression of tyrosinase-related proteins (TYRP-1 and TYRP-2) and Endothelin-1 (ET-1).In another preferred embodiment of the invention, the use of said cosmetic composition to combat melasma is described.
