A male reflux valve for use with an IV line, container or the like to preclude fluid from escaping therefrom unless and until the proximal body portion of the valve is accessed by an access device, whereupon fluid is allowed to flow bi-directionally through the valve. The valve consists of a proximal body portion, a distal body portion, a core or holder placed within the distal body portion, a valve element or septum placed within the core to provide a seal, and an actuator placed within the proximal body portion configured to engage with the valve element when the male end of the valve is connected to a female engaging member.
