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L-ornithine phenyl acetate and methods of making thereof
专利权人:
OCERA THERAPEUTICS INC.
发明人:
Behling Jim,Dougan Christine Henderson,Figini Attilia,Watt Stephen William,Anderson Keith,Manini Peter
申请号:
NZ70845810
公开号:
NZ708458A
申请日:
2010.04.01
申请国别(地区):
NZ
年份:
2017
代理人:
摘要:
Disclosed is a process for making L-ornithine phenyl acetate salt comprising: increasing the pH value of a solution comprising an L-ornithine salt at least until an intermediate salt precipitates, wherein said intermediate salt is not an L-ornithine salt; isolating the intermediate salt from said solution; intermixing phenyl acetic acid with said solution; and isolating L-ornithine phenyl acetate salt from said solution. Also disclosed is the L-ornithine phenyl acetate salt prepared by this process. L-ornithine phenyl acetate is useful in the treatment of hyperammonemia.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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