Parvinder Pal Singh,Gurunadham Munagala,Reddy Yempalla Kushalava,Inshad Ali Khan,Nitin Pal Kalia,Vikrant Singh Rajput,Amit Nargotra,Sanghapal Damodhar Sawant,Ram Asray Vishwakarma
申请号:
US15027137
公开号:
US09845330B2
申请日:
2014.03.31
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention relates to newer generation of triazoles, tetrazoles, isoxazoles, urea and sulphonamide functionalities containing 6-nitro-2,3-dihydronitroimidazooxazoles agents of formula 1, their method of preparation, and their use as drugs for treating Mycobacterium tuberculosis, MDR-TB and XDR-TB either alone or in combination with other anti-tubercular agents. In the present invention, new generation 6-nitro-2,3-dihydronitroimidazooxazoles agents also show acceptable pharmacokinetic properties and synergistic or additive effects with known anti-tubercular drugs.