6-NITRO-2,3-DIHYDROIMIDAZO[2,1-B]OXAZOLES AND A PROCESS FOR THE PREPARATION THEREOF

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专利权人:

COUNCIL SCIENT IND RES

发明人:

申请号：

EP14725544.2

公开号：

EP3052503B1

申请日:

2014.03.31

申请国别(地区):

EP

年份:

2018

代理人:

摘要：

The present invention relates to newer generaration of triazoles, tetrazoles, isoxazoles, urea and sulphonamide functionalities containing 6-nitro-2, 3-dihydronitroimidazooxazoles agents, their method of preparation, and to their use as drugs for treating Mycobacterium tuberculosis, MDR-TB and XDR-TB either alone or in combination with other anti-tubercular agents. In the present invention, new generaration 6-nitro-2,3-dihydronitroimidazooxazoleasg ents also shown acceptable pharmacokinetic properties and synergistic or additive effects with known anti-tubercular drugs.

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