INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM);INSTITUT PASTEUR
发明人:
REYRAT, JEAN-MARC,BAY, SYLVIE,BIET, FRANCK
申请号：
NZ58547608
公开号：
NZ585476A
申请日:
2008.10.24
申请国别(地区):
NZ
年份:
2012
代理人:
摘要：
The use of a Mycobacterium paratuberculosis antigen for the in vitro detection of anti-M. paratuberculosis antibodies from a biological sample. The antigen is (a) a synthetic peptide 5P having the formula DPhe-NMeVal-Ile-Phe-Ala-OMe (SEQ ID NO:1) or (b) a lipopeptide L5P that consists of SEQ ID NO:1 wherein the N-terminal phenylalanine residue is N-acylated with an eicosanoic acid acyl chain. The antigen can be used to detect a delayed-type hypersensitivity cell-mediated immune response against M. paratuberculosis.
