MYNTTI, MATTHEW F.,OLIVER, DANA A.,VACCARO, BRIAN J.
申请号:
CA2721986
公开号:
CA2721986C
申请日:
2009.04.23
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
Tissue and other body structures may be protected using a hydrated compositionmade from free-flowing substantiallycollagen-free rehydratable polysaccharide particles and rehydratablepolysaccharide sponges. Rehydration of the particleswithout clumping may be carried out be dispersing the particles in abiocompatible water-miscible polar dispersant such as ethanoland combining the dispersion with sufficient aqueous solvent for the particlesto convert them to a cohesive hydrogel. The hydratedcomposition may assist in returning an injured, inflamed or surgicallyrepaired surface to a normal state, e.g., through one ormore healing mechanisms such as modulation of an inflammatory response,phagocytosis, mucosal remodeling, reciliation orother full or partial restoration of normal function.