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Use of 2,5-dihydroxybenzenesulfonic acid in the manufacture of a medicament for the treatment of vascular dependent diseases such as cancer and psoriasis
专利权人:
ファーマシューティカルズ、エルエルシー;アムデルマ
发明人:
クエバス サンチェス、ペドロ,ロメロ ガリド、アントニオ,ロサノ プエルト、ローサ マリア,ヒメネス ガリェゴ、ギリェルモ,バルベルデ ロペス、セラフィン
申请号:
JP2014205125
公开号:
JP5973518B2
申请日:
2014.10.03
申请国别(地区):
JP
年份:
2016
代理人:
摘要:
The invention relates to the use of 2,5-dihydroxybenzenesulfonic acid in the production of medicaments for the treatment of angiodependent diseases. More specifically, the invention relates to the use of the aforesaid compound and, in particular, the calcium and potassium salts thereof, for the treatment of two angiodependent diseases, which present a reduction in the apoptosis, namely cancer and psoriasis. The invention also discloses the antiproliferative, antimigratory, antiangiogenic and proapoptotic capacity of said family of compounds in non-quiescent cells. In addition, the invention details the potentiating effect of said compounds on known cytostatic medicines in the treatment of tumours and, specifically, on gliomas. The invention further relates to the therapeutic efficacy of said compounds, based on the combined antiproliferative, antiangiogenic and proapaptotic capacities threof, in the treatment of chronic psoriatic plaques.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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