6-Phenyl-1H-imidazo [4,5-c] pyridine-4-carbonitrile derivatives as cathepsin inhibitors

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专利权人:

エム・エス・ディー・オス・ベー・フェー

发明人:

ツアイ，チアチアン,ランコビツチ，ゾラン,ジヨーンズ、フイリツプ・ステイーブン,ベンネツト，デイビツド・ジヨナサン,フラデラ，ハビエル,ツアイ,チアチアン,ランコビツチ,ゾラン,ベンネツト,デイビツド・ジヨナサン,フラデラ,ハビエル

申请号：

JP2010516481

公开号：

JP5371976B2

申请日:

2008.07.14

申请国别(地区):

JP

年份:

2013

代理人:

摘要：

The present invention relates to 6-phenyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile derivatives having the general Formula (I), to pharmaceutical compositions comprising the same as well as to the use of these derivatives for the preparation of a medicament for the treatment of cathepsin S related diseases such asatherosclerosis,obesity, inflammation and immune disorders, such as rheumatoid arthritis, psoriasis, cancer,and chronic pain, such as neuropathic pain.

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