The present invention provides a therapeutic composition comprising one or more polyphenols and two or more carotenoids selected from the group consisting of lutein, lycopene and beta-carotene, wherein the polyphenols are selected from the group consisting of resveratrol, curcumin, quercetin, gallic acid, gingerol and chicoric acid. The invention also provides this composistion for use in inhibiting or reducing the production of superoxide ions, NO, TNF-alpha and/or PGE 2 or for treating an inflammatory condition in a mammalian subject.
