THE PROCTER & GAMBLE COMPANY;THE CLEVELAND CLINIC FOUNDATION
发明人:
HAZEN, STANLEY LEON,GARCIA-GARCIA, JOSE CARLOS,GERBERICK, GEORGE FRANKLIN,WOS, JOHN AUGUST,STANTON, DAVID THOMAS,INGLIN, THOMAS ALFRED,REILLY, MICHAEL,DEUTSCH, ANGELA JANE,REED, JODIE MICHELLE,CODY, D
申请号:
CA3007061
公开号:
CA3007061A1
申请日:
2016.12.01
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
The invention provides a method of inhibiting the conversion of carnitine to trimethylamine (TMA) and lowering TMAO in an individual comprising administering to the individual one or more compositions comprising a compound set forth in Formula (I) wherein the compound is administered in an amount effective to inhibit conversion of carnitine to TMA in the individual.