The Procter & Gamble Company;The Cleveland Clinic Foundation
发明人:
Hazen, Stanley Leon,Garcia-Garcia, Jose Carlos,Gerberick, George Franklin,Wos, John August,Stanton, David Thomas,Inglin, Thomas Alfred,Reilly, Michael,Deutsch, Angela Jane,Reed, Jodie Michelle,Cody, D
申请号:
AU2016365316
公开号:
AU2016365316B2
申请日:
2016.12.01
申请国别(地区):
AU
年份:
2019
代理人:
摘要:
The invention provides a method of inhibiting the conversion of carnitine to trimethylamine (TMA) and lowering TMAO in an individual comprising administering to the individual one or more compositions comprising a compound set forth in Formula (I) wherein the compound is administered in an amount effective to inhibit conversion of carnitine to TMA in the individual.