[Problem] Provided is a pharmaceutical, in particular, a pharmaceutical composition which is useful for the treatment of pain. [Means for Solution] The present inventors have made extensive studies using model animals with pain for the purpose of providing a therapeutic agent for pain. As a result, they have found that 11²-hydroxydehydrogenase type 1 (11²-HSD1) inhibitor, in particular, a triazole compound having a cyclic group at the 3-position (or 5-position) of a triazole ring has a good effect of ameliorating chronic pain. That is, according to the present invention, a pharmaceutical composition comprising an 11²-HSD1 inhibitor, in particular, the triazole compound of the present invention, as an active ingredient, is useful for the treatment of pain (particularly, neuropathic pain or fibromyalgia).本發明係關於提供一種醫藥上，特別在疼痛治療上有用的醫藥組成物。本發明者們將疼痛治療劑的提供作為目的，使用疼痛模型動物進行詳細檢討。其結果發現11β-羥基脫氫酶型1(11β-HSD1)阻礙劑，特別於三唑環的第3位(或第5位)上具有環基為特徵之三唑化合物可顯示良好慢性疼痛改善效果。即，本發明係以11β-HSD1阻礙劑，特別為含有本發明三唑化合物作為有效成分之醫藥組成物於疼痛(特別為神經障礙性疼痛、纖維肌疼痛症)的治療上有用。
