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Therapeutic agent for pain
专利权人:
Tetsuo Kiso;Mina Tsukamoto
发明人:
Tetsuo Kiso,Mina Tsukamoto
申请号:
US13820873
公开号:
US09765040B2
申请日:
2011.09.06
申请国别(地区):
US
年份:
2017
代理人:
摘要:
[Problem]Provided is a pharmaceutical, in particular, a pharmaceutical composition which is useful for the treatment of pain.[Means for Solution]The present inventors have made extensive studies using model animals with pain for the purpose of providing a therapeutic agent for pain. As a result, they have found that 11β-hydroxydehydrogenase type 1 (11β-HSD1) inhibitor, in particular, a triazole compound having a cyclic group at the 3-position (or 5-position) of a triazole ring has a good effect of ameliorating chronic pain. That is, according to the present invention, a pharmaceutical composition comprising an 11β-HSD1 inhibitor, in particular, the triazole compound of the present invention, as an active ingredient, is useful for the treatment of pain (particularly, neuropathic pain or fibromyalgia).
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