BRIAN METCALF,WENQING YAO,JINCONG ZHUO,MEIZHONG XU,CHUNHONG HE,DING-QUAN QIAN,COLIN ZHANG
申请号:
PT05745656
公开号:
PT1756063E
申请日:
2005.05.04
申请国别(地区):
PT
年份:
2015
代理人:
摘要:
The present invention relates to inhibitors of 11-² hydroxyl steroid dehydrogenase type 1, antagonists of the mineralocorticoid receptor (MR), and pharmaceutical compositions thereof. The compounds of the invention can be useful in the treatment of various diseases associated with expression or activity of 11-² hydroxyl steroid dehydrogenase type 1 and/or diseases associated with aldosterone excess.