HOWARD CHRISTOPHER BRUCE,RALSTON KYLIE JANE,WARD LINDA ALLISON,VAN HEUMEN WALTER RENE ANTONIUS,STOK JEANETTE ELIZABETH,DE BAKKER CHRISTOPHER JOHN,JAMES ANDREW LEIGH,NAYLOR DEAN JASON,BROWN RICHARD JAM
申请号:
NZ59966610
公开号:
NZ599666A
申请日:
2010.10.08
申请国别(地区):
NZ
年份:
2014
代理人:
摘要:
Disclosed is an isolated chaperonin 10 (Cpn10) variant polypeptide sharing at least 90% sequence identity with a wild-type Cpn10 polypeptide comprising a sequence as defined herein wherein said polypeptide has increased binding affinitiy for a pathogen-associatred molecular pattern (PAMP) or has increased immunomodulatory function.