STEROL REGULATORY ELEMENT BINDING PROTEIN (SREBP) CHAPERONE (SCAP) iRNA COMPOSITIONS AND METHODS OF USE THEREOF

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专利权人:

Alnylam Pharmaceuticals; Inc.

发明人:

Kevin Fitzgerald,Huilei Xu,Gregory Hinkle

申请号：

US16002034

公开号：

US20180273955A1

申请日:

2018.06.07

申请国别(地区):

US

年份:

2018

代理人:

摘要：

The invention relates to double stranded ribonucleic acid (dsRNAi) agents and compositions targeting the SCAP gene, as well as methods of inhibiting expression of a SCAP gene and methods of treating subjects having a SCAP-associated disorder, such as nonalcoholic fatty liver disease (NAFLD) or nonalcoholic steatohepatitis (NASH), using such dsRNAi agents and compositions.

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