A sheath adapter configured for use between a tissue puncture closure device and a procedural sheath, the procedural sheath adapted for insertion into a tissue puncture, and the tissue puncture closure device adapted for partial insertion into the procedural sheath and sealing of the tissue puncture, the sheath adapter comprising: a sheath connection portion positioned at a distal end of the sheath adapter; a closure device connection portion positioned at a proximal end of the sheath adapter; an aperture sized for passage of a carrier tube of the tissue puncture closure device through the sheath adapter.