WANG, MENG,YANG, ZIZHEN,RADA, CRISTINA,NEUBERGER, MICHAEL
申请号:
DK10723293
公开号:
DK2414507T3
申请日:
2010.04.05
申请国别(地区):
DK
年份:
2014
代理人:
摘要:
The invention provides functional mutants of activation-induced cytidine deaminase (AID) protein that have increased activity as compared to a wild-type AID protein. The invention also provides nucleic acids encoding the functional AID mutants, and vectors and cells comprising the nucleic acids. The invention further provides methods of using the functional mutant AID proteins.