WANG, MENG,YANG, ZIZHEN,RADA, CRISTINA,NEUBERGER, MICHAEL
申请号:
CA2757178
公开号:
CA2757178C
申请日:
2010.04.05
申请国别(地区):
CA
年份:
2020
代理人:
摘要:
The invention provides functional mutants of activation-induced cytidinedeaminase (AID) protein that have increasedactivity as compared to a wild-type AID protein. The invention also providesnucleic acids encoding the functional AIDmutants, and vectors and cells comprising the nucleic acids. The inventionfurther provides methods of using the functional mutantAID proteins.