JAESCHKE, GEORG,LINDEMANN, LOTHAR,RICCI, ANTONIO,RUEHER, DANIEL,STADLER, HEINZ,VIEIRA, ERIC
申请号:
SG11201401322U
公开号:
SG11201401322UA
申请日:
2012.10.04
申请国别(地区):
SG
年份:
2014
代理人:
摘要:
The present invention relates to ethynyl derivatives of formula I wherein U, V, Y, R1, R2, R2′, R3, R3′ and R8 are described herein. It has been found that the compounds of general formula I are allosteric modulators of the metabotropic glutamate receptor subtype 5 (mGluR5).