ETHYNYL DERIVATES AS MGLUR5 ALLOSTERIC MODULATORS

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专利权人:

F.HOFFMANN-LA ROCHE AG

发明人:

JAESCHKE GEORG,RICCI,ANTONIO,STADLER,HEINZ,LINDEMANN,LOTHAR,RUEHER,DANIEL,VIEIRA,ERIC

申请号：

ZA201402069

公开号：

ZA201402069B

申请日:

2014.03.20

申请国别(地区):

ZA

年份:

2015

代理人:

摘要：

The present invention relates to ethynyl derivatives of formula I wherein U, V, Y, R1, R2, R2&prime；, R3, R3&prime； and R8 are described herein. It has been found that the compounds of general formula I are allosteric modulators of the metabotropic glutamate receptor subtype 5 (mGluR5).

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中国工程科技知识中心

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