A medical compression garment is provided including a midline opening cut in a medial segment of the elastic garment, dividing its front fabric portion into first and second sections. Fasteners, such as hook-and-loop fasteners, are attached to the first and second sections which connect together to close the opening. Pulls may be included. To don the garment, a wearer places their legs into the garment and pulls the garment along the legs until its top is aligned with the groin. The wearer then inverts and pulls the first and second sections of the garment together and fastens them to close the opening. Afterwards, the wearer pulls up the garment until it reaches the waist. When the wearer subsequently wants to take off the garment, the wearer unfastens the first and second sections and pull the garment down from the waist. The garment thus facilitates the donning and removal process.