Subhra Mohapatra,Shyam S. Mohapatra,Mark Christian Howell,Suraj Kishore Dixit,Chunyan Wang
申请号：
US13773749
公开号：
US20130243867A1
申请日:
2013.02.22
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Provided herein is a micelle composition comprising a polyethylene glycol (PEG), a DC-cholesterol, and a dioleoylphosphatidyl-ethanolamine (DOPE) and either or both a pharmaceutical compound core and a polynucleotide coating. Also provided herein is a method of administering one or more compounds to a cell comprising administering to the cell a micelle composition comprising 1) PEG-PE, a DC-cholesterol, and DOPE, and 2) the one or more compounds, wherein the compounds are selected from the group consisting of a polynucleotide and a pharmaceutical composition. Further provided are methods for detecting the micelle composition.
