PROBLEM TO BE SOLVED: To provide a technique for sending a target substance, concretely a physiologically active substance, to an intracellular organelle selectively among of early endosome (1), late endosome (2) and lysosome (3) and discharge the substance in the inside and to provide concretely a carrier for the technique and its use.SOLUTION: A composition containing a compound expressed by either one of following formulas DL-G1 to DL-G4: DL-G1 of R1R2NX(XHR3)XHR4 DL-G2 of R1R2NX(X(XHR3)XHR4)2 DL-G3 of R1R2NX(X(X(XHR3)XHR4)2)2 and DL-G4 of R1R2NX(X(X(X(XHR3)XHR4)2)2)2.COPYRIGHT: (C)2014,JPO&INPIT【課題】目的物、具体的には生理活性物質、を(1)初期エンドソーム、(2)後期エンドソーム及び(3)リソソームのいずれかの細胞内オルガネラに選択的に送達してその内部で放出しうる手段を提供すること、すなわち具体的には当該手段としてのキャリア、及びその使用方法等を提供する。【解決手段】下記式DL-G1~DL-G4のいずれかで表される化合物を含有する遺伝子導入用組成物。DL-G1:R1R2NX(XHR3)XHR4DL-G2:R1R2NX(X(XHR3)XHR4)2DL-G3:R1R2NX(X(X(XHR3)XHR4)2)2DL-G4:R1R2NX(X(X(X(XHR3)XHR4)2)2)2【選択図】なし
