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PYRAZOLOPYRIDINE DERIVATIVES AS NADPH-OXIDASE INHIBITORS
- 专利权人:
- ZHENKIOTEKS SA
- 发明人:
- PAZh Patrik (FR),ПАЖ Патрик (FR),OChARD Majk (GB),ОЧАРД Майк (GB),LALE Benua (FR),ЛАЛЁ Бенуа (FR),GADZhINI Francheska (CH),ГАДЖИНИ Франческа (CH),PAZH PATRIK,ПАЖ Патрик,OCHARD MAJK,ОЧАРД Майк,LALE BENUA,ЛАЛЁ Бенуа,GADZHINI FRANCHESKA,ГАДЖИНИ Франческа
- 申请号：
- RU2011116230/04
- 公开号：
- RU0002538041C2
- 申请日:
- 2009.09.22
- 申请国别(地区):
- RU
- 年份:
- 2015
- 代理人:
- 摘要：
- FIELD: medicine, pharmaceutics.SUBSTANCE: invention refers to pyrazolopyridine derivatives of formula (I) , a based pharmaceutical composition, and using them for treating and/or preventing disorders or conditions related to nictonamide adenine dinucleotide phosphatoxidase (NADPH-oxidase), as well as to a method for preparing them and an intermediate of formula (VIII) . In general formula (I), G1 is specified in H； and optionally substituted heteroaryl-C1-C6-alkyl； G2 is specified in H； optionally substituted C1-C6-alkyl； optionally substituted C2-C6-alkenyl； optionally substituted C2-C6-alkinyl； optionally substituted aryl； optionally substituted C1-C6-alkylaryl； optionally substituted aryl-C1-C6-alkyl； optionally substituted heteroaryl； optionally substituted C1-C6-alkylheteroaryl； optionally substituted heteroaryl-C1-C6-alkyl； optionally substituted C2-C6-alkenylaryl； optionally substituted aryl-C2-C6-alkenyl； optionally substituted C2-C6-alkenylheteroaryl； optionally substituted heteroaryl-C2-C6-alkenyl； optionally substituted C3-C8-cycloalkyl； optionally substituted C3-C8-heterocycloalkyl； optionally substituted C1-C6-alkyl-C3-C8-cycloalkyl； optionally substituted C3-C8-cycloalkyl-C1-C6-alkyl； optionally substituted C1-C6-alkyl-C3-C8-heterocycloalkyl and optionally substituted C3-C8-heterocycloalkyl-C1-C6-alkyl； G3 is specified in H； optionally substituted amino； optionally substituted aminoalkyl； optionally substituted aminocarbonyl； optionally substituted alkoxy, optionally substituted alkoxy-C1-C6-alkyl； optionally substituted carbonyl； optionally substituted C1-C6-alkyl； optionally substituted C2-C6-alkenyl； optionally substituted C2-C6-alkinyl； optionally substituted aryl； optionally substituted aryl-C1-C6-alkyl； optionally substituted C1-C6-alkylaryl: optionally substituted heteroaryl； optionally substituted C1-C6-alkylheteroaryl； optionally substituted heteroaryl-C1-C6-alkyl； optionally substituted C2-C6-alkenylaryl； optionally substituted aryl-C2-C6-alk
- 来源网站：
- 中国工程科技知识中心
- 来源网址：
- http://www.ckcest.cn/home/
