The invention relates to a decontamination device, in particular for pharmaceutical use, comprising at least one space 4 to be decontaminated, in particular an isolator space, preferably a manipulator space and / or a plenum space separated by a membrane from the manipulator space. A decontamination apparatus, comprising a valve means 27 having a decontamination liquid reservoir 36, from which the decontamination liquid reservoir is controllable by electronic control means to various atomizers A, B, C, D. Decontamination liquid, preferably hydrogen peroxide, can be supplied, and the atomizer is arranged in the space 4 to be decontaminated and preferably configured as a two-material nozzle, and serves to generate decontamination aerosols, The atomizers A, B, C, D are fluidly connected to the ring line 32 via the valve means 27, the ring line having an inlet 33 and an outlet 34 separated from the inlet, and contaminated Remove liquid low Cattle and the decontamination liquid from (36) can be passed to the inlet of the ring line by means of a pump (35), the decontamination liquid from the outlet of the ring line can be returned to the decontamination liquid reservoir 36, and flow； The ring line 32 is assigned a pressure regulating means 37 for maintaining the liquid pressure in the ring line 32 in a predetermined liquid pressure range. According to the invention, there are provided measuring means 40 for determining the total amount of decontamination liquid delivered to the atomizers A, B, C, D during the decontamination cycle, which measuring means is in particular a decontamination liquid reservoir. Gravimetric means 41 for determining the amount of decontamination liquid in 36.본 발명은 오염 제거될 적어도 하나의 공간(4), 특히 격리기 공간, 바람직하게는 조작기 공간 및/또는 조작기 공간으로부터 막에 의해 분리된 플리넘 공간을 포함하는 오염 제거 장치, 특히 제약 용도를 위한 오염 제거 장치에 관한 것으로, 오염 제거 액체 저장소(36)를 구비하고, 이 오염 제거 액체 저장소로부터, 여러 아토마이저(A, B, C, D)에 전자 제어 수단에 의해 제어 가능한 밸브 수단(27)을 통해 오염 제거 액체, 바람직하게는 과산화수소가 공급될 수 있고, 아토마이저는 오염 제거될 공간(4) 내에 배열되고
