COMPOSITION COMPRENANT DES DÉRIVÉS DE BENPROPÉRINE EN TANT QUE PRINCIPES ACTIFS POUR LA PRÉVENTION ET LE TRAITEMENT DE MALADIES ASSOCIÉES À L'ANGIOGENÈSE
Korea Research Institute of Bioscience and Biotechnology
发明人:
申请号：
EP11839421.2
公开号：
EP2638910A2
申请日:
2011.11.11
申请国别(地区):
EP
年份:
2013
代理人:
摘要：
The present invention relates to a novel pharmaceutical composition of benproperine derivatives for preventing and treating angiogenesis-related diseases. The benproperine derivatives and pharmaceutically acceptable salts thereof according to the present invention inhibit cancer cell migration and the angiogenesis of vascular endothelial cells, and therefore can be effectively used not only as an anticancer agent, but also as an agent for preventing and treating diseases caused by abnormal angiogenesis, such as diabetic retinopathy and corneal transplant rejection.
